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Topic hub

Peptide Science

Foundational articles on how peptides are built and how they behave in research systems, plus compound-by-compound overviews that summarize the published evidence and its limits.

Peptide Science

What Is a Peptide? A Plain-Language Primer for Researchers

Peptides sit between single amino acids and full proteins. Here is how they are defined, how they are built, and why chain length changes everything about handling and stability.

August 24, 2026 · 6 min read

Peptide Science

What Is an Amino Acid?

Twenty proteinogenic residues, one shared backbone, and side chains that decide charge, solubility and stability. A short structural primer for laboratory work.

August 22, 2026 · 5 min read

Peptide Science

How Signaling Peptides Work

Most research peptides are messengers, not building material. Here is the receptor-level logic behind why a short sequence can produce a large downstream effect.

August 20, 2026 · 7 min read

Peptide Science

Receptor Pathways Primer

Binding affinity, efficacy, desensitisation and biased signalling — the four concepts that explain most surprises in peptide receptor work.

August 18, 2026 · 6 min read

Peptide Science

Amino Acid Signaling and Receptor Biology

Amino acids are not only building blocks — several are signals in their own right, sensed by receptors and nutrient-sensing complexes inside the cell.

August 16, 2026 · 5 min read

Peptide Science

The Science Behind Cellular Signaling

From ligand binding to gene transcription: how a signal at the cell surface becomes a lasting change inside the nucleus.

August 14, 2026 · 6 min read

Peptide Science

What Is a GLP-1 Receptor Agonist?

The incretin axis, why native GLP-1 lasts only minutes, and how modern analogues are engineered to survive far longer.

August 12, 2026 · 7 min read

Compound Reviews

Retatrutide vs Tirzepatide vs Semaglutide

One receptor, two receptors, or three. A structural and pharmacological comparison of the three most-studied incretin analogues.

August 10, 2026 · 8 min read

Compound Reviews

BPC-157 Research: Mechanism, Evidence and Open Questions

A pentadecapeptide fragment studied heavily in animal models. What the mechanism work describes, and where the human evidence gap sits.

August 8, 2026 · 7 min read

Compound Reviews

TB-500 and Thymosin Beta-4: What the Research Describes

TB-500 is a fragment, not the full protein. The distinction matters for how the published thymosin beta-4 literature should be read.

August 6, 2026 · 6 min read

Compound Reviews

GHK-Cu: The Copper Tripeptide, Reviewed

Three residues and one copper ion. Why the metal is part of the molecule, and what the dermatological and gene-expression literature actually reports.

August 4, 2026 · 6 min read

Peptide Science

A Short History of Peptide Research

From Fischer's peptide bond to solid-phase synthesis to engineered multi-receptor analogues — a century of method driving discovery.

August 3, 2026 · 6 min read

Compound Reviews

MOTS-c: A Mitochondrial-Derived Peptide

Encoded in mitochondrial DNA rather than the nuclear genome, MOTS-c sits at the centre of research on metabolic stress signalling.

August 2, 2026 · 6 min read

Compound Reviews

Humanin: The First Mitochondrial-Derived Peptide

Discovered in a screen for cytoprotective factors, humanin remains the reference case for mitochondrial-derived peptide biology.

July 30, 2026 · 5 min read

Compound Reviews

Ipamorelin: A Selective Growth Hormone Secretagogue

Ipamorelin is studied because of what it does not do — a ghrelin receptor agonist with a notably narrow reported off-target profile.

July 28, 2026 · 5 min read

Compound Reviews

Selank and Semax: Shared Design, Different Parent Peptides

Two Russian-developed research peptides built on the same stabilising strategy — and why that shared tail is a synthesis decision, not a shared mechanism.

July 26, 2026 · 6 min read

Compound Reviews

Cagrilintide: A Long-Acting Amylin Analogue

Amylin is co-secreted with insulin and signals satiety through the brainstem. Cagrilintide is the engineered, long-duration version studied alongside incretin compounds.

July 24, 2026 · 6 min read